Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 18/20 | 0.58 |
| ▸ | TRPC4 | Q9UBN4 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329825 | 0.88 | TRPC5 (0.56) | TRPC5TRPC4KCNH2PTPN11 | |
| SCHEMBL29090307 | 0.87 | TRPC5 (0.70) | TRPC5TRPC4KCNH2 | |
| SCHEMBL29329996 | 0.87 | TRPC5 (0.56) | TRPC5TRPC4KCNH2 | |
| SCHEMBL29329986 | 0.87 | TRPC5 (0.56) | TRPC5TRPC4KCNH2 | |
| SCHEMBL29329994 | 0.87 | TRPC5 (0.56) | TRPC5TRPC4KCNH2 | |
| SCHEMBL22002418 | 0.83 | TRPC5 (0.77) | TRPC5TRPC4KCNH2 | |
| SCHEMBL29090312 | 0.78 | TRPC5 (0.56) | TRPC5TRPC4KCNH2TIPARP | |
| SCHEMBL29330209 | 0.77 | TRPC5 (0.59) | TRPC5TRPC4TIPARP | |
| SCHEMBL29329354 | 0.77 | TRPC5 (0.59) | TRPC5TRPC4TIPARP | |
| SCHEMBL22002481 | 0.77 | TRPC5 (0.64) | TRPC5TRPC4KCNH2TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |