Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 10/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330954 | 0.87 | APP (0.38) | APP | |
| SCHEMBL29330719 | 0.80 | APP (0.35) | APP | |
| SCHEMBL29330499 | 0.80 | APP (0.35) | APP | |
| SCHEMBL30938624 | 0.80 | CSNK1A1 (0.41) | APP | |
| SCHEMBL29330958 | 0.80 | CSNK1A1 (0.41) | APP | |
| SCHEMBL31312439 | 0.79 | CHRM4 (0.40) | APPTYK2 | |
| SCHEMBL29330570 | 0.78 | APP (0.36) | APP | |
| SCHEMBL29331093 | 0.78 | KDM4E (0.35) | APPEGFRTYK2 | |
| SCHEMBL29330496 | 0.78 | GAA (0.34) | APPEGFR | |
| SCHEMBL29330502 | 0.77 | KCNH2 (0.39) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |