SCHEMBL29330570

SCHEMBL29330570

N#Cc1cc(OCC2CC(F)(F)C2)cc(Nc2ccc3c(F)c[nH]c3c2)n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.36
CACNA1H O95180 3/20 0.35
MET P08581 1/20 0.34
IDH1 O75874 1/20 0.32
BRAF P15056 1/20 0.31
KDR P35968 1/20 0.31
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29331093 0.82 KDM4E (0.35) APPMET
SCHEMBL29330566 0.81 IMPDH2 (0.50) MET
SCHEMBL29330842 0.81 IMPDH2 (0.36) APPMET
SCHEMBL30938599 0.80 APP (0.33) APPMETKDR
SCHEMBL29330496 0.80 GAA (0.34) APPMET
SCHEMBL29331089 0.79 MET (0.37) APPMETBRAF
SCHEMBL29330500 0.79 P2RY14 (0.35) APP
SCHEMBL29329212 0.79 LRRK2 (0.36) METIDH1LRRK2
SCHEMBL30938641 0.78 APP (0.31) APPMET
SCHEMBL30938624 0.78 CSNK1A1 (0.41) APPMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151919-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM DUE, INC. (US) 2024-07-18 WO disclosed