Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 13/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.45 |
| ▸ | CDK7 | P50613 | 5/20 | 0.45 |
| ▸ | CCNH | P51946 | 4/20 | 0.45 |
| ▸ | CDK4 | P11802 | 5/20 | 0.41 |
| ▸ | CCND1 | P24385 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | CDK3 | Q00526 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331385 | 0.82 | CDK9 (0.44) | CDK9CCNT1CDK7CCNHCDK4 | |
| SCHEMBL30992013 | 0.76 | CDK9 (0.45) | CDK9CCNT1CDK7CCNHCDK4 | |
| SCHEMBL29330772 | 0.76 | CDK9 (0.45) | CDK9CCNT1CDK7CCNHCDK4 | |
| SCHEMBL29331388 | 0.75 | CDK9 (0.47) | CDK9CCNT1CDK7CCNHCDK4 | |
| Hydrochloric Acid SCHEMBL30991915 | 0.69 | CDK9 (0.50) | CDK9CCNT1CDK7CCNHCDK4 | |
| SCHEMBL29332433 | 0.67 | CDK9 (0.41) | CDK9CCNT1CDK7CCNHCDK4 | |
| Hydrochloric Acid SCHEMBL30991916 | 0.66 | CDK9 (0.43) | CDK9CCNT1CDK7CCNHCDK4 | |
| Hydrochloric Acid SCHEMBL30991892 | 0.66 | CDK9 (0.41) | CDK9CCNT1CDK7CCNHCDK4 | |
| SCHEMBL30991957 | 0.64 | CDK9 (0.40) | CDK9CCNT1CDK7CCNHCDK4 | |
| SCHEMBL29333254 | 0.64 | CDK9 (0.48) | CDK9CCNT1CDK7CCNHCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151112-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR | 주식회사 티움바이오 | 2024-07-18 | — | — | WO | disclosed |