SCHEMBL2933260

SCHEMBL2933260

Clc1ccc(Cl)c(-c2c(Cl)ccc(Cl)c2Cl)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.45
MAPK1 P28482 1/20 0.45
CES1 P23141 3/20 0.42
CYP2A6 P11509 2/20 0.39
ALDH1A1 P00352 1/20 0.39
AHR P35869 5/20 0.38
CYP1A2 P05177 1/20 0.37
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CYP1B1 Q16678 1/20 0.35
PNMT P11086 1/20 0.33
NOTUM Q6P988 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29915258 1.00 CYP3A4 (0.45) CYP3A4MAPK1CES1CYP2A6ALDH1A1
SCHEMBL29367755 0.90 CYP3A4 (0.39) CYP3A4MAPK1CES1CYP2A6ALDH1A1
SCHEMBL4454468 0.90 CYP3A4 (0.39) CYP3A4MAPK1CES1CYP2A6ALDH1A1
SCHEMBL30542156 0.87 CYP3A4 (0.47) CYP3A4MAPK1CES1ALDH1A1AHR
SCHEMBL4447158 0.87 TSHR (0.48) CYP3A4MAPK1CES1CYP2A6ALDH1A1
SCHEMBL23827191 0.87 CYP3A4 (0.47) CYP3A4MAPK1CES1ALDH1A1AHR
SCHEMBL29816658 0.87 TSHR (0.48) CYP3A4MAPK1CES1CYP2A6ALDH1A1
SCHEMBL29389611 0.85 ALDH1A1 (0.50) CYP3A4MAPK1CES1ALDH1A1AHR
SCHEMBL4459139 0.85 ALDH1A1 (0.50) CYP3A4MAPK1CES1ALDH1A1AHR
SCHEMBL4459037 0.83 CYP3A4 (0.50) CYP3A4MAPK1CES1ALDH1A1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed