Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 19/20 | 0.62 |
| ▸ | MELK | Q14680 | 1/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23267470 | 0.94 | BCL6 (0.59) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267149 | 0.93 | BCL6 (0.65) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267504 | 0.93 | BCL6 (0.65) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267505 | 0.93 | BCL6 (0.65) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267037 | 0.92 | BCL6 (0.64) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267519 | 0.91 | BCL6 (0.59) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267472 | 0.91 | BCL6 (0.59) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267138 | 0.91 | BCL6 (0.63) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267750 | 0.91 | BCL6 (0.64) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267093 | 0.91 | BCL6 (0.64) | BCL6MELKNCOR2CHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151557-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |