Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 20/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.64 |
| ▸ | MELK | Q14680 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284555 | 0.95 | BCL6 (0.66) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL24717367 | 0.94 | BCL6 (0.65) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267470 | 0.91 | BCL6 (0.59) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267035 | 0.91 | BCL6 (0.61) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267139 | 0.91 | BCL6 (0.77) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267504 | 0.90 | BCL6 (0.65) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267505 | 0.90 | BCL6 (0.65) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267472 | 0.90 | BCL6 (0.59) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL24717538 | 0.90 | BCL6 (0.62) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL29333173 | 0.90 | BCL6 (0.62) | BCL6NCOR2MELKCHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151557-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |