Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333364 | 1.00 | NR4A2 (0.41) | NR4A2SLC6A3L3MBTL1HSD17B10GAA | |
| SCHEMBL20563399 | 0.80 | NR4A2 (0.48) | NR4A2SLC6A3L3MBTL1HSD17B10GAA | |
| SCHEMBL257244 | 0.79 | NR4A2 (0.51) | NR4A2SLC6A3L3MBTL1HSD17B10GAA | |
| SCHEMBL29827082 | 0.79 | NR4A2 (0.51) | NR4A2SLC6A3L3MBTL1HSD17B10GAA | |
| SCHEMBL26984344 | 0.78 | PDE5A (0.47) | NR4A2SLC6A3POLB | |
| SCHEMBL31156118 | 0.77 | NR4A2 (0.45) | NR4A2SLC6A3L3MBTL1HSD17B10HTT | |
| SCHEMBL5236111 | 0.76 | KMT2A (0.46) | NR4A2SLC6A3L3MBTL1HSD17B10GAA | |
| SCHEMBL31275511 | 0.75 | HDAC11 (0.44) | HSD17B10ALDH1A1FAAHCNR2MAPT | |
| SCHEMBL8512059 | 0.74 | NR4A2 (0.47) | NR4A2SLC6A3L3MBTL1HSD17B10GAA | |
| SCHEMBL516923 | 0.73 | ALPL (0.47) | NR4A2SLC6A3L3MBTL1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |