Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088677 | 0.73 | CCNE2 (0.51) | — | |
| SCHEMBL27088683 | 0.73 | CCNE2 (0.51) | — | |
| SCHEMBL27089334 | 0.73 | CCNE2 (0.51) | — | |
| SCHEMBL23767749 | 0.69 | — | — | |
| SCHEMBL8264800 | 0.65 | CXCR2 (0.39) | PDCD1LG2CD274TNF | |
| SCHEMBL29322201 | 0.62 | PDCD1LG2 (0.40) | PDCD1LG2CD274 | |
| SCHEMBL15360304 | 0.62 | ALDH1A1 (0.39) | — | |
| SCHEMBL27089257 | 0.61 | PDCD1LG2 (0.39) | PDCD1LG2CD274SLC6A4 | |
| SCHEMBL27089288 | 0.61 | PDCD1LG2 (0.39) | PDCD1LG2CD274SLC6A4 | |
| SCHEMBL27088681 | 0.61 | PDCD1LG2 (0.39) | PDCD1LG2CD274SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228512-A1 | ACYCLIC OXAZEPINE COMPOUNDS COMPRISING A 6-AZA MOIETY AND USES THEREOF | GENENTECH, INC. (US) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228512-A1 | ACYCLIC OXAZEPINE COMPOUNDS COMPRISING A 6-AZA MOIETY AND USES THEREOF | AZI2, HDAC5, HDAC4 | PDCD1LG2 388/4885CD274 775/4885SLC6A4 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.