SCHEMBL29335251

SCHEMBL29335251

COC1CN([C@H]2CC[C@@H](I)CC2)C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29335250 1.00 IRAK4 (0.33) IRAK4
SCHEMBL24921073 0.89
SCHEMBL26619666 0.84 IRAK4 (0.35) IRAK4
SCHEMBL24315776 0.81 IRAK4 (0.32) IRAK4
SCHEMBL25921366 0.80 KDM4E (0.33) IRAK4
SCHEMBL24718088 0.80 KDM4E (0.33) IRAK4
SCHEMBL25921408 0.80 KDM4E (0.33) IRAK4
SCHEMBL26823952 0.79 HRH3 (0.34) IRAK4
SCHEMBL12409015 0.79 HRH3 (0.34) IRAK4
SCHEMBL22351882 0.78 LMNA (0.33) IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151557-A1 MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. (US) 2024-07-18 WO disclosed