SCHEMBL29335408

SCHEMBL29335408

C=CCOC(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 1/20 0.41
▸ FURIN P09958 3/20 0.40
▸ BACE1 P56817 1/20 0.40
▸ SIRT2 Q8IXJ6 9/20 0.39
▸ SIRT1 Q96EB6 8/20 0.39
▸ SIRT3 Q9NTG7 3/20 0.39
▸ SIRT5 Q9NXA8 3/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16198012 0.91 HTT (0.42) HTTFURINBACE1SIRT2SIRT1
SCHEMBL31713913 0.88 FURIN (0.44) HTTFURINSIRT2SIRT1SIRT3
SCHEMBL16801698 0.87 FURIN (0.39) HTTFURINSIRT5SMN1; SMN2
SCHEMBL12094324 0.86 FURIN (0.39) HTTFURINSIRT2SIRT1SIRT3
SCHEMBL23286090 0.86 HTT (0.41) HTTFURINSIRT2SIRT1SIRT3
SCHEMBL13814439 0.86 SIRT2 (0.55) SIRT2SIRT1SIRT3SIRT5
SCHEMBL22387920 0.86 SIRT2 (0.55) SIRT2SIRT1SIRT3SIRT5
SCHEMBL17312925 0.86 FURIN (0.39) HTTFURINSMN1; SMN2
SCHEMBL23680473 0.85 HTT (0.40) HTTFURINSIRT2SIRT1SIRT3
SCHEMBL22283146 0.85 SIRT2 (0.40) BACE1SIRT2SIRT1SIRT3SIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041776-A1 POLYMER CONTRAST AGENT KOWA COMPANY, LTD. (JP) 2026-02-12 — — US disclosed
EP-4570837-A1 POLYMER CONTRAST AGENT KOWA COMPANY, LTD. (JP) 2025-06-18 — — EP disclosed
US-20240261426-A1 CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY BYONDIS B.V. (NL) 2024-08-08 — — US disclosed
WO-2024150132-A1 LIGAND-DRUG CONJUGATES SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-07-18 — — WO disclosed
EP-4362982-A1 CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY Byondis B.V. (NL) 2024-05-08 — — EP disclosed
WO-2023275025-A1 CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY BYONDIS B.V. (NL) 2023-01-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041776-A1 POLYMER CONTRAST AGENT RXFP3, HAX1, MSR1 HTT 2576/4885FURIN 3777/4885BACE1 4058/4885
US-20240261426-A1 CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY CD47, PTMS, PAG1 HTT 3683/4885FURIN 487/4885BACE1 2354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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