SCHEMBL29336502

SCHEMBL29336502

C=CCN(C)Cc1ccc(C)cc1

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 2/20 0.70
LSS P48449 3/20 0.51
CNR2 P34972 2/20 0.44
CNR1 P21554 1/20 0.44
NPSR1 Q6W5P4 1/20 0.41
KCNH2 Q12809 2/20 0.40
C5AR1 P21730 1/20 0.39
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11526241 0.86 PYCR1 (0.52) PYCR1LSSCNR2CNR1C5AR1
SCHEMBL29336506 0.82 PYCR1 (1.00) PYCR1LSS
SCHEMBL9442713 0.82 PYCR1 (0.68) PYCR1LSS
SCHEMBL185582 0.82 PYCR1 (0.67) PYCR1LSS
SCHEMBL16312619 0.80 PYCR1 (0.65) PYCR1NPSR1KCNH2CYP2C19
Hydrochloric Acid SCHEMBL251246 0.80 PYCR1 (0.65) PYCR1LSS
SCHEMBL29336500 0.79 PYCR1 (0.64) PYCR1LSSKCNH2
SCHEMBL9149606 0.79 PYCR1 (0.54) PYCR1LSS
SCHEMBL20871858 0.77 CNR2 (0.49) PYCR1CNR2CNR1KCNH2C5AR1
SCHEMBL11181366 0.77 PYCR1 (0.57) PYCR1NPSR1KCNH2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3707132-B1 NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES UNIV PARIS SACLAY (FR) 2024-07-17 EP disclosed