SCHEMBL29336775

SCHEMBL29336775

CCOC(=N)c1cccc(Oc2ccc3[nH]ccc3n2)c1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 18/20 0.47
▸ F2 P00734 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29336702 0.83 F10 (0.64) F10F2
SCHEMBL29337674 0.79 MAP4K4 (0.49) —
SCHEMBL30285529 0.78 F10 (0.43) F10F2
SCHEMBL29336846 0.77 F10 (0.41) F10F2
SCHEMBL30285654 0.77 F10 (0.41) F10F2
SCHEMBL29336675 0.73 MAP4K4 (0.52) —
SCHEMBL31176868 0.72 F10 (0.41) F10F2
SCHEMBL3736270 0.72 AKR1C3 (0.54) F10F2
Hydrochloric Acid SCHEMBL3736269 0.70 AKR1C3 (0.53) F10F2
SCHEMBL29336928 0.70 F10 (0.40) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239784-A1 INDOLE COMPOUNDS AND METHODS OF USE GENZYME CORPORATION 2024-07-18 — — US disclosed
US-20240239784-A1 INDOLE COMPOUNDS AND METHODS OF USE GENZYME CORPORATION 2024-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239784-A1 INDOLE COMPOUNDS AND METHODS OF USE CFTR, INMT, IDO1 F10 3750/4885F2 2919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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