Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.31 |
| ▸ | ALB | P02768 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13787902 | 0.84 | LOXL2 (0.41) | TAAR1ADRA2CLOXL2CYP19A1FFAR1 | |
| Hydrochloric Acid SCHEMBL5047133 | 0.83 | LOXL2 (0.40) | TAAR1ADRA2CLOXL2CYP19A1EGLN2 | |
| SCHEMBL27847324 | 0.81 | CYP19A1 (0.35) | TAAR1CYP19A1FFAR1FFAR4EGLN2 | |
| SCHEMBL12184920 | 0.76 | CYP2A6 (0.41) | LOXL2CYP19A1EGLN2TTRALB | |
| SCHEMBL20967889 | 0.76 | CYP11B1 (0.33) | CYP19A1FFAR1FFAR4EGLN2TTR | |
| SCHEMBL17864267 | 0.76 | TTR (0.37) | CYP19A1EGLN2TTRALBMEN1 | |
| SCHEMBL536576 | 0.76 | EPAS1 (0.37) | TAAR1CYP19A1FFAR1FFAR4EGLN2 | |
| SCHEMBL603677 | 0.76 | TTR (0.37) | CYP19A1EGLN2TTRALBMEN1 | |
| SCHEMBL17514977 | 0.76 | TTR (0.32) | CYP19A1EGLN2TTRALBMEN1 | |
| SCHEMBL14538279 | 0.75 | MAOB (0.45) | TAAR1LOXL2CYP19A1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |