Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786644 | 0.83 | KMT2A (0.42) | KMT2AL3MBTL1KCNH2 | |
| SCHEMBL20738685 | 0.82 | KMT2A (0.41) | KMT2AL3MBTL1KCNH2 | |
| SCHEMBL17791881 | 0.77 | SLC1A3 (0.47) | KMT2AL3MBTL1 | |
| SCHEMBL8462131 | 0.74 | KMT2A (0.39) | KMT2AL3MBTL1KCNH2 | |
| SCHEMBL458565 | 0.74 | — | — | |
| SCHEMBL1356569 | 0.73 | KMT2A (0.46) | KMT2AL3MBTL1 | |
| SCHEMBL24169103 | 0.72 | TLR7 (0.41) | KMT2AL3MBTL1KCNH2 | |
| SCHEMBL256680 | 0.72 | — | — | |
| SCHEMBL25156787 | 0.72 | — | — | |
| SCHEMBL13476170 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |