Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627288 | 0.78 | SLC13A5 (0.46) | ALDH1A1PTGS2 | |
| SCHEMBL3627285 | 0.78 | SLC13A5 (0.46) | ALDH1A1PTGS2 | |
| Hydrochloric Acid SCHEMBL540304 | 0.77 | ALDH1A1 (0.46) | ALDH1A1PTGS2 | |
| Hydrochloric Acid SCHEMBL27850090 | 0.77 | ALDH1A1 (0.46) | ALDH1A1PTGS2 | |
| SCHEMBL28704258 | 0.73 | MIF (0.39) | ALDH1A1PTGS2ANPEP | |
| SCHEMBL23480895 | 0.73 | CYP11B1 (0.36) | ALDH1A1PTGS2 | |
| SCHEMBL29063413 | 0.73 | CYP11B1 (0.36) | ALDH1A1PTGS2 | |
| SCHEMBL8462131 | 0.72 | KMT2A (0.39) | KMT2AL3MBTL1KDM4CHPGDHPGDS | |
| SCHEMBL5401318 | 0.71 | ALDH1A1 (0.47) | ALDH1A1PTGS2 | |
| SCHEMBL24158724 | 0.71 | KMT2A (0.46) | KMT2AL3MBTL1KDM4CHPGDSP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281869-A1 | TETRAHYDROISOQUINOLINES AS ANTIMALARIAL AGENTS | AISSAOUI HAMED (FR) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281869-A1 | TETRAHYDROISOQUINOLINES AS ANTIMALARIAL AGENTS | QTRT2, RECQL, QTRT1 | KMT2A 865/4885L3MBTL1 4369/4885KDM4C 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.