Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.70 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28244500 | 1.00 | TAAR1 (0.70) | TAAR1IDO1AGXTTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11695113 | 0.98 | TAAR1 (0.68) | TAAR1IDO1AGXTTSHRMAPK1 | |
| SCHEMBL29194747 | 0.88 | TAAR1 (0.72) | TAAR1IDO1AGXTAOC3SLC6A4 | |
| SCHEMBL30762190 | 0.85 | TAAR1 (0.72) | TAAR1IDO1AGXTAOC3CHRM2 | |
| SCHEMBL13349231 | 0.85 | TAAR1 (0.72) | TAAR1IDO1AGXTAOC3SLC6A4 | |
| SCHEMBL4572890 | 0.85 | TAAR1 (0.72) | TAAR1IDO1AGXTAOC3CHRM2 | |
| (S)-M-Methoxyamphetamine SCHEMBL3293027 | 0.82 | TAAR1 (1.00) | TAAR1IDO1AGXTSLC6A4 | |
| SCHEMBL11694237 | 0.82 | PCNA (0.45) | TAAR1SLC6A4 | |
| (S)-M-Methoxyamphetamine SCHEMBL30813013 | 0.82 | TAAR1 (1.00) | TAAR1IDO1AGXTSLC6A4 | |
| (S)-M-Methoxyamphetamine SCHEMBL11461072 | 0.82 | TAAR1 (1.00) | TAAR1IDO1AGXTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |