Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 2/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19151578 | 0.82 | NOS3 (0.46) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL20738702 | 0.81 | HTT (0.41) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL24925771 | 0.80 | HTT (0.43) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL18793683 | 0.79 | NOS3 (0.48) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL24375835 | 0.79 | CCR1 (0.46) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL507316 | 0.79 | CCR1 (0.46) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL25170530 | 0.79 | NOS3 (0.48) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL507079 | 0.79 | CCR1 (0.46) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL29793597 | 0.79 | NOS3 (0.48) | NOS3NOS2HTTRECQLCCR1 | |
| SCHEMBL1509600 | 0.79 | NOS3 (0.48) | NOS3NOS2HTTRECQLCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |