Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608020 | 1.00 | PDE2A (0.44) | PDE2ALMNATP53HTTTRPA1 | |
| SCHEMBL10155650 | 1.00 | PDE2A (0.44) | PDE2ALMNATP53HTTTRPA1 | |
| SCHEMBL26345780 | 1.00 | PDE2A (0.44) | PDE2ALMNATP53HTTTRPA1 | |
| Hydrochloric Acid SCHEMBL29199836 | 0.98 | PDE2A (0.43) | PDE2ALMNATP53HTTTRPA1 | |
| Hydrochloric Acid SCHEMBL29199838 | 0.98 | PDE2A (0.43) | PDE2ALMNATP53HTTTRPA1 | |
| SCHEMBL20811584 | 0.83 | PDE2A (0.58) | PDE2ALMNATP53HTTTRPA1 | |
| SCHEMBL17767222 | 0.83 | PDE2A (0.58) | PDE2ALMNATP53HTTTRPA1 | |
| SCHEMBL17769044 | 0.83 | PDE2A (0.58) | PDE2ALMNATP53HTTTRPA1 | |
| SCHEMBL84060 | 0.82 | TRPA1 (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL20790467 | 0.81 | PDE2A (0.56) | PDE2ALMNATP53HTTTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |