Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034411 | 1.00 | AKR1B1 (0.33) | AKR1B1SMN1; SMN2DYRK1AHTTKMT2A | |
| SCHEMBL7921143 | 0.80 | CCR1 (0.31) | — | |
| SCHEMBL21178473 | 0.79 | NPC1 (0.31) | SMN1; SMN2HTTKMT2A | |
| SCHEMBL30001346 | 0.79 | NPC1 (0.31) | SMN1; SMN2HTTKMT2A | |
| SCHEMBL21178512 | 0.79 | HTT (0.34) | DYRK1AHTTKMT2A | |
| SCHEMBL27198200 | 0.78 | RIPK1 (0.34) | — | |
| SCHEMBL14305624 | 0.73 | AKR1B1 (0.38) | AKR1B1DYRK1A | |
| SCHEMBL31378896 | 0.72 | AKR1B1 (0.42) | AKR1B1 | |
| SCHEMBL25551298 | 0.72 | RIPK1 (0.48) | AKR1B1KMT2A | |
| SCHEMBL25551352 | 0.72 | RIPK1 (0.48) | AKR1B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148191-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |