Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 6/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19640288 | 1.00 | HMGCR (0.43) | HMGCRPTPN7TSHRKDM4EALDH1A1 | |
| SCHEMBL3030008 | 0.90 | HMGCR (0.49) | HMGCRPTPN7TSHRRECQLTDP1 | |
| SCHEMBL10540472 | 0.90 | HMGCR (0.49) | HMGCRPTPN7TSHRRECQLTDP1 | |
| SCHEMBL28437823 | 0.90 | HMGCR (0.49) | HMGCRPTPN7TSHRRECQLTDP1 | |
| SCHEMBL1533719 | 0.84 | HMGCR (0.42) | HMGCRPTPN7TSHRKDM4EALDH1A1 | |
| SCHEMBL4763127 | 0.82 | HMGCR (0.33) | HMGCRTSHR | |
| SCHEMBL6852096 | 0.82 | — | — | |
| SCHEMBL11180416 | 0.81 | HMGCR (0.43) | HMGCRPTPN7TSHRRECQLTDP1 | |
| SCHEMBL8157636 | 0.81 | HMGCR (0.41) | HMGCRPTPN7RECQLTDP1 | |
| SCHEMBL8385155 | 0.80 | HMGCR (0.44) | HMGCRPTPN7TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229399-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF | Provid Pharmaceuticals, Inc. (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009073168-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF | PROVID PHARMACEUTICALS, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| EP-1974013-A2 | IMPROVED COMPOSITION FOR COLLECTING AND PRESERVING PLACENTAL STEM CELLS AND METHODS OF USING THE COMPOSITION | Anthrogenesis Corporation (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079185-A2 | IMPROVED COMPOSITION FOR COLLECTING AND PRESERVING PLACENTAL STEM CELLS AND METHODS OF USING THE COMPOSITION | ANTHROGENESIS CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |