Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19640288 | 0.82 | HMGCR (0.43) | HMGCRTSHR | |
| SCHEMBL2933749 | 0.82 | HMGCR (0.43) | HMGCRTSHR | |
| SCHEMBL6820171 | 0.81 | HMGCR (0.33) | HMGCRTSHR | |
| SCHEMBL8893382 | 0.81 | HMGCR (0.33) | HMGCRTSHR | |
| SCHEMBL5813803 | 0.80 | — | — | |
| SCHEMBL6852096 | 0.79 | — | — | |
| SCHEMBL8385155 | 0.77 | HMGCR (0.44) | HMGCRTSHR | |
| SCHEMBL1533719 | 0.76 | HMGCR (0.42) | HMGCRTSHR | |
| SCHEMBL3030008 | 0.74 | HMGCR (0.49) | HMGCRTSHR | |
| SCHEMBL29012576 | 0.74 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1927594-A1 | 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia | Arena Pharmaceuticals, Inc. (US) | 2008-06-04 | — | — | EP | disclosed |