SCHEMBL2933847

SCHEMBL2933847

NC(=S)NNc1cccc2c1C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.53
MAPT P10636 5/20 0.53
HPGD P15428 2/20 0.53
MEN1 O00255 2/20 0.53
HTT P42858 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP2C19 P33261 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
SMAD3 P84022 1/20 0.53
PRMT1 Q99873 1/20 0.53
ACE2 Q9BYF1 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 4/20 0.51
ALOX12 P18054 2/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 1/20 0.51
BRCA1 P38398 1/20 0.51
HSD17B10 Q99714 1/20 0.51
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10841402 0.84 FTO (0.57) FTOMAPTHPGDMEN1HTT
SCHEMBL9427763 0.83 FTO (0.54) FTOMAPTHPGDMEN1HTT
SCHEMBL22334359 0.83 FTO (0.54) FTOMAPTHPGDMEN1HTT
SCHEMBL15759875 0.83 FTO (0.54) FTOMAPTHPGDMEN1HTT
SCHEMBL9280412 0.82 FTO (0.59) FTOMAPTHPGDMEN1HTT
SCHEMBL1362510 0.82 FTO (0.55) FTOMAPTHPGDMEN1HTT
SCHEMBL9428188 0.81 FTO (0.56) FTOMAPTHPGDMEN1HTT
SCHEMBL9428563 0.81 FTO (0.56) FTOMAPTHPGDMEN1HTT
SCHEMBL19426565 0.81 FTO (0.51) FTOMAPTHPGDMEN1HTT
SCHEMBL9157669 0.81 FTO (0.53) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443329-B1 A method for simultaneously performing a plurality of assays ABBOTT LAB (US) 2010-09-15 EP disclosed
EP-0746769-B1 AUTOMATED CONTINUOUS AND RANDOM ACCESS ANALYTICAL METHOD ABBOTT LAB (US) 2006-09-06 EP disclosed
EP-1666888-A2 A method of operating an automated analytical system Abbott Laboratories (US) 2006-06-07 EP disclosed
EP-1205756-B1 Automated liquid level sensing system and method ABBOTT LAB (US) 2006-04-12 EP disclosed
EP-1028320-B1 Method of operating an automated, continuous and random access analytical system capable of simultaneously effecting multiple assays in a plurality of liquid samples ABBOTT LAB (US) 2006-03-01 EP disclosed
EP-1537915-A2 Reaction vessel ABBOTT LABORATORIES (US) 2005-06-08 EP disclosed
EP-1450162-A2 Cartridge feeder apparatus ABBOTT LABORATORIES (US) 2004-08-25 EP disclosed
EP-1450161-A2 Automatic closure of containers ABBOTT LABORATORIES (US) 2004-08-25 EP disclosed
EP-1450163-A2 Syringe with bubble flushing ABBOTT LABORATORIES (US) 2004-08-25 EP disclosed
EP-1443329-A2 A method for simultaneously performing a plurality of assays Abbott Laboratories (US) 2004-08-04 EP disclosed
US-5376313-A Injection molding a plastic assay cuvette having low birefringence ABBOTT LABORATORIES (US) 1994-12-27 US disclosed
US-5358691-A Automated continuous and random access analytical system ABBOTT LABORATORIES (US) 1994-10-25 US disclosed
US-5340750-A Reagents and methods for the quantification of imipramine or desipramine in biological fluids ABBOTT LABORATORIES (US) 1994-08-23 US disclosed
EP-0599935-A1 REAGENTS AND METHODS FOR THE QUANTIFICATION OF AMITRIPTYLINE OR NORTRIPTYLINE IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES (US) 1994-06-08 EP disclosed
WO-1993019928-A1 PLASTIC ASSAY CUVETTE HAVING LOW BIREFRINGENCE ABBOTT LABORATORIES (US) 1993-10-14 WO disclosed
WO-1993020443-A1 ASSAY VERIFICATION CONTROL FOR ANALYTICAL METHODS ABBOTT LABORATORIES (US) 1993-10-14 WO disclosed
WO-1993020440-A1 AUTOMATED CONTINUOUS AND RANDOM ACCESS ANALYTICAL SYSTEM AND COMPONENTS THEREOF ABBOTT LABORATORIES (US) 1993-10-14 WO disclosed
WO-1993020444-A1 METHODS FOR PROVIDING HOMOGENEOUS REAGENTS ABBOTT LABORATORIES (US) 1993-10-14 WO disclosed
WO-1993003371-A1 REAGENTS AND METHODS FOR THE QUANTIFICATION OF IMIPRAMINE OR DESIPRAMINE IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES (US) 1993-02-18 WO disclosed
WO-1993003370-A1 REAGENTS AND METHODS FOR THE QUANTIFICATION OF AMITRIPTYLINE OR NORTRIPTYLINE IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES (US) 1993-02-18 WO disclosed