Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231713 | 0.82 | CRBN (0.60) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30702623 | 0.82 | CRBN (0.60) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30694261 | 0.82 | CRBN (0.60) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL31728131 | 0.82 | CRBN (0.60) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL20211856 | 0.80 | CRBN (0.65) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL29547243 | 0.80 | CRBN (0.65) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL20046071 | 0.80 | CRBN (0.65) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL20211890 | 0.80 | CRBN (0.65) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL22498051 | 0.80 | CRBN (0.59) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL24718246 | 0.80 | IKZF1 (0.48) | CRBNIKZF2CSNK1A1DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151557-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |