SCHEMBL29338809

SCHEMBL29338809

CN(Cc1ccccc1)[C@H]1CCC(O)C1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 0.54
GRIN2B Q13224 1/20 0.48
AGTR2 P50052 2/20 0.47
HRH4 Q9H3N8 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
SLC6A4 P31645 1/20 0.43
NAAA Q02083 2/20 0.43
JAK2 O60674 1/20 0.43
JAK1 P23458 1/20 0.43
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3375289 0.84 GRIN2B (0.61) SLC18A3GRIN2BHRH4HRH3NAAA
SCHEMBL29182197 0.83 YTHDC1 (0.49) SLC18A3GRIN2BSLC6A4ALDH1A1TSHR
SCHEMBL25111999 0.83 YTHDC1 (0.49) SLC18A3GRIN2BSLC6A4ALDH1A1TSHR
SCHEMBL25341885 0.83 YTHDC1 (0.49) SLC18A3GRIN2BSLC6A4ALDH1A1TSHR
SCHEMBL29182199 0.83 YTHDC1 (0.49) SLC18A3GRIN2BSLC6A4ALDH1A1TSHR
SCHEMBL23329113 0.83 YTHDC1 (0.49) SLC18A3GRIN2BSLC6A4ALDH1A1TSHR
SCHEMBL15970179 0.80 GRIN2B (0.48) SLC18A3GRIN2BAGTR2HRH4HRH3
SCHEMBL28115401 0.80 SLC18A3 (0.50) SLC18A3GRIN2BAGTR2HRH4HRH3
SCHEMBL28115399 0.80 SLC18A3 (0.50) SLC18A3GRIN2BAGTR2HRH4HRH3
SCHEMBL11251947 0.78 HRH3 (0.67) SLC18A3GRIN2BHRH4HRH3NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400497-A1 3CLPRO PROTEASE INHIBITOR Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) 2024-07-17 EP disclosed