SCHEMBL29338998

SCHEMBL29338998

N#Cc1ccccc1Sc1cc(-c2cnn(C(F)F)c2)cn2ncc(C#N)c12

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RET P07949 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31130890 1.00 RET (0.52) RET
SCHEMBL31131285 0.90 RET (0.51) RET
SCHEMBL31130910 0.87 RET (0.44) RET
SCHEMBL29338670 0.87 RET (0.44) RET
SCHEMBL29339171 0.85 RET (0.45) RET
SCHEMBL31130845 0.85 RET (0.45) RET
SCHEMBL31131196 0.84 RET (0.40) RET
SCHEMBL29339135 0.84 RET (0.40) RET
SCHEMBL31131199 0.84 RET (0.52) RET
SCHEMBL29338346 0.84 RET (0.52) RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151638-A2 COMPOUNDS FOR FGFRS INHIBITORS COGENT BIOSCIENCES, INC. (US) 2024-07-18 WO disclosed