Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18793714 | 0.75 | ALDH1A1 (0.39) | ROCK1MEN1KMT2A | |
| SCHEMBL29340328 | 0.73 | AAK1 (0.41) | ROCK1HIF1ADGAT1LIPGPRMT5 | |
| SCHEMBL17939899 | 0.71 | ROCK1 (0.52) | ROCK1HIF1ADGAT1LIPGPRMT5 | |
| SCHEMBL20562631 | 0.71 | PDE4D (0.42) | ROCK1HIF1ADGAT1LIPGPRMT5 | |
| SCHEMBL17939955 | 0.69 | HIF1A (0.42) | ROCK1HIF1ADGAT1LIPGPRMT5 | |
| SCHEMBL19510675 | 0.69 | ROCK1 (0.41) | ROCK1HIF1ADGAT1LIPGLTA4H | |
| SCHEMBL20562401 | 0.69 | HIF1A (0.44) | ROCK1HIF1ADGAT1LIPGPRMT5 | |
| SCHEMBL27176829 | 0.69 | HIF1A (0.48) | ROCK1HIF1ADGAT1LIPGPRMT5 | |
| SCHEMBL14711661 | 0.69 | ROCK1 (0.44) | ROCK1HIF1ADGAT1LIPGPRMT5 | |
| SCHEMBL14274291 | 0.69 | ROCK1 (0.47) | ROCK1HIF1ADGAT1LIPGCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |