Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 19/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 9/20 | 0.46 |
| ▸ | CDK2 | P24941 | 8/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29343631 | 0.73 | MAPK1 (0.63) | MAPK1 | |
| SCHEMBL29341894 | 0.73 | MAPK1 (0.63) | MAPK1MAPK3 | |
| SCHEMBL29343703 | 0.72 | MAPK1 (0.61) | MAPK1MAPK3 | |
| SCHEMBL18794310 | 0.72 | MAPK1 (0.65) | MAPK1MAPK3 | |
| SCHEMBL29344797 | 0.72 | MAPK1 (0.62) | MAPK1MAPK3 | |
| SCHEMBL18794026 | 0.70 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL18765867 | 0.70 | MAPK1 (0.78) | MAPK1MAPK3 | |
| SCHEMBL26073368 | 0.69 | CDK1 (0.46) | MAPK1CDK2CCNA2CCNT1CCNC | |
| SCHEMBL18794517 | 0.68 | MAPK1 (0.60) | MAPK1MAPK3CCNT1CDK9 | |
| SCHEMBL18793968 | 0.68 | MAPK1 (1.00) | MAPK1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |