Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612831 | 0.84 | MAPT (0.74) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL30040053 | 0.83 | ELANE (0.61) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL26187210 | 0.83 | ELANE (0.61) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL11266728 | 0.83 | EGFR (0.56) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL11271335 | 0.83 | EGFR (0.56) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL30610014 | 0.83 | ELANE (0.61) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL29339204 | 0.83 | ELANE (0.58) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL29339918 | 0.82 | EGFR (0.55) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL29338964 | 0.82 | EGFR (0.55) | EGFRPIM1MEN1KMT2AMAPT | |
| SCHEMBL3417492 | 0.82 | EGFR (0.76) | EGFRPIM1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151672-A1 | DIRECTED BIOSYNTHESIS OF MODIFIED ANTHRAQUINONE-FUSED ENEDIYNES AS POTENTIAL CANCER THERAPEUTICS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-18 | — | — | WO | disclosed |