SCHEMBL612831

SCHEMBL612831

COc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.74
MEN1 O00255 5/20 0.74
KMT2A Q03164 5/20 0.74
ALDH1A1 P00352 5/20 0.74
TDP1 Q9NUW8 3/20 0.74
KDM4E B2RXH2 2/20 0.74
USP2 O75604 1/20 0.74
DUSP3 P51452 1/20 0.74
EGFR P00533 2/20 0.69
PIM1 P11309 1/20 0.69
RAB9A P51151 6/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
NPC1 O15118 2/20 0.66
ELANE P08246 4/20 0.61
ADORA2A P29274 3/20 0.61
POLB P06746 2/20 0.61
MAPK1 P28482 2/20 0.61
FGB P02675 1/20 0.61
THRB P10828 1/20 0.61
PPARG P37231 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435387 0.94 MAPT (0.70) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL3417492 0.94 EGFR (0.76) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL9264626 0.92 MAPT (0.74) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL8947495 0.92 EGFR (0.73) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL7792566 0.90 EGFR (0.71) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL10974170 0.88 EGFR (0.74) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL28569052 0.88 MAPT (0.68) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL4015824 0.88 MEN1 (0.68) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL29595070 0.86 MAPT (0.66) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL28573446 0.86 MAPT (0.66) MAPTMEN1KMT2AALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101344-A Laser welding polyphenyl ether alloy and preparation method thereof 广东兴盛迪科技有限公司 2024-12-10 CN claimed
US-20220372355-A1 METHOD FOR MAKING AGGLOMERATE PARTICLES MCARDLE JAMES L (US) 2022-11-24 US claimed
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 EP claimed
US-11203706-B1 Method for making agglomerate particles AMERIPOLISH INC. (US) 2021-12-21 US claimed
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH ZURICH (CH) 2021-06-24 US claimed
CN-112794932-A Method for improving enzymolysis performance of lignocellulose biomass through pretreatment 江南大学 2021-05-14 CN claimed
EP-3801507-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2021-04-14 EP claimed
US-20170298209-A1 USE OF A QUINONE COMPOUND IN BUILDING MATERIALS ARKION LIFE SCIENCES, LLC (US) 2017-10-19 US claimed
CN-103993364-B A kind of method aoxidizing degumming raising ramee performance 东华大学 2016-10-12 CN claimed
CN-103866950-B Cement matrix prestressing force composite floor board and preparation method thereof BEIHUA UNIVERSITY (CN) 2016-04-06 CN claimed
US-20150208657-A1 USE OF QUINONE COMPOUND IN BUILDING MATERIALS ARKION LIFE SCIENCES, LLC (US) 2015-07-30 US claimed
EP-1745000-A2 NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF Michigan State University (US) 2007-01-24 EP claimed
US-20050267307-A1 Novel anthraquinones and process for the preparation and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-12-01 US claimed
WO-2005113478-A2 NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF MICHIGAN STATE UNIVERSITY (US) 2005-12-01 WO claimed
US-6638356-B2 Gypsum as the main material and an anthraquinone compound incorporated. And suppresses, over a long period of time, generation of hydrogen sulfide by the action of sulfate-reducing bacteria, when it is landfilled as waste. KAWASAKI KASEI CHEMICALS LTD. (JP) 2003-10-28 US claimed
US-4351774-A Process for the production of methoxyanthraquinones CIBA-GEIGY AG (CH) 1982-09-28 US claimed
EP-0010451-A1 Process for the delignification of lignocellulosic material and products thereof C.I.L. Inc. (CA) 1980-04-30 EP claimed
US-4080370-A Process for producing high purity methoxyanthraquinones MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JA) 1978-03-21 US claimed
CN-116635452-B Free radically polymerizable crosslinking agent, curable composition, and adhesive therefrom 3M INNOVATIVE PROPERTIES CO. (US) 2026-05-26 CN disclosed
US-3953408-A LITHOGRAPHIC PLATES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050267307-A1 Novel anthraquinones and process for the preparation and method of use thereof PAH, APEH, SDHA MAPT 3904/4885MEN1 1208/4885KMT2A 758/4885
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION TOMM70, TOMM34, TIMM50 MAPT 2071/4885MEN1 2055/4885KMT2A 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.