Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948105 | 1.00 | USP30 (0.44) | USP30FFAR1JAK1JAK2KDM1A | |
| SCHEMBL22086042 | 0.92 | USP30 (0.44) | USP30FFAR1JAK1JAK2KDM1A | |
| SCHEMBL16876545 | 0.84 | FFAR1 (0.44) | USP30FFAR1JAK1JAK2AAK1 | |
| SCHEMBL31009816 | 0.82 | FFAR1 (0.41) | USP30FFAR1AAK1PIK3CAPRMT5 | |
| SCHEMBL29339875 | 0.82 | FFAR1 (0.41) | USP30FFAR1AAK1PIK3CAPRMT5 | |
| SCHEMBL320828 | 0.81 | USP30 (0.52) | USP30FFAR1JAK2IRAK4DDB1 | |
| SCHEMBL21916132 | 0.81 | FFAR1 (0.41) | USP30FFAR1AAK1PRMT5WDR77 | |
| SCHEMBL659798 | 0.80 | CHRM2 (0.44) | USP30FFAR1DDB1CRBNHSD11B1 | |
| SCHEMBL29548160 | 0.80 | CHRM2 (0.44) | USP30FFAR1DDB1CRBNHSD11B1 | |
| SCHEMBL26702696 | 0.80 | CHRM2 (0.44) | USP30FFAR1DDB1CRBNHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |