SCHEMBL31009816

SCHEMBL31009816

CN(C(=O)OC(C)(C)C)C1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 1/20 0.41
▸ USP30 Q70CQ3 2/20 0.39
▸ BACE1 P56817 1/20 0.38
▸ BACE2 Q9Y5Z0 1/20 0.38
▸ DDB1 Q16531 1/20 0.34
▸ CRBN Q96SW2 1/20 0.34
▸ SPR P35270 4/20 0.33
▸ KDM4D Q6B0I6 1/20 0.33
▸ DGAT1 O75907 1/20 0.32
▸ HSD11B1 P28845 1/20 0.31
▸ PRMT5 O14744 1/20 0.31
▸ WDR77 Q9BQA1 1/20 0.31
▸ KAT6A Q92794 1/20 0.31
▸ KAT8 Q9H7Z6 1/20 0.31
▸ AAK1 Q2M2I8 1/20 0.31
▸ CCNC P24863 1/20 0.31
▸ CDK8 P49336 1/20 0.31
▸ PIK3R1 P27986 1/20 0.31
▸ PIK3CA P42336 1/20 0.31
▸ GPR119 Q8TDV5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29339875 1.00 FFAR1 (0.41) FFAR1USP30BACE1BACE2DDB1
SCHEMBL21630478 0.92 FFAR1 (0.41) FFAR1USP30BACE1BACE2DDB1
SCHEMBL21630479 0.92 FFAR1 (0.41) FFAR1USP30BACE1BACE2DDB1
SCHEMBL16876545 0.84 FFAR1 (0.44) FFAR1USP30BACE1BACE2DDB1
SCHEMBL3948105 0.82 USP30 (0.44) FFAR1USP30DDB1CRBNHSD11B1
SCHEMBL29339874 0.82 USP30 (0.44) FFAR1USP30DDB1CRBNHSD11B1
SCHEMBL320828 0.81 USP30 (0.52) FFAR1USP30BACE1DDB1CRBN
SCHEMBL21916132 0.81 FFAR1 (0.41) FFAR1USP30BACE1BACE2DDB1
SCHEMBL659798 0.80 CHRM2 (0.44) FFAR1USP30BACE1BACE2DDB1
SCHEMBL29548160 0.80 CHRM2 (0.44) FFAR1USP30BACE1BACE2DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4648763-A2 COMPOUNDS FOR FGFRS INHIBITORS Cogent Biosciences, Inc. (US) 2025-11-19 — — EP disclosed
WO-2024151638-A2 COMPOUNDS FOR FGFRS INHIBITORS COGENT BIOSCIENCES, INC. (US) 2024-07-18 — — WO disclosed
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