SCHEMBL29340263

SCHEMBL29340263

O=Cc1cc(Cl)cc(F)c1CBr

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.44
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1139983 0.80 TSHR (0.35)
SCHEMBL28892459 0.75 ERN1 (0.50) ERN1TDP1
SCHEMBL30474266 0.74 ALDH1A1 (0.36)
SCHEMBL30402820 0.74 ERN1 (0.52) ERN1TDP1
SCHEMBL20798249 0.74 ERN1 (0.52) ERN1TDP1
SCHEMBL24095329 0.72 ALDH1A1 (0.31)
SCHEMBL29956081 0.72 ERN1 (0.75) ERN1
SCHEMBL27127807 0.72 ERN1 (0.31) ERN1
SCHEMBL3664243 0.72 ERN1 (0.75) ERN1
SCHEMBL20670942 0.71 ERN1 (0.48) ERN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365334-B1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS OTSUKA PHARMA CO LTD (JP) 2024-07-17 EP disclosed