SCHEMBL29340583

SCHEMBL29340583

Cc1c(C)c2ccc(-c3ccc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)cc3)nc2c2ncccc12

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
HSP90AA1 P07900 1/20 0.53
TOP1 P11387 4/20 0.42
CCR1 P32246 2/20 0.42
CCR8 P51685 2/20 0.42
CYP19A1 P11511 1/20 0.42
DHODH Q02127 3/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CCR5 P51681 1/20 0.38
PPARA Q07869 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
SLC40A1 Q9NP59 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29340581 0.96 NPC1 (0.51) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29340586 0.96 NPC1 (0.51) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29340584 0.96 L3MBTL1 (0.54) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29340580 0.96 L3MBTL1 (0.58) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29340576 0.96 L3MBTL1 (0.58) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29340578 0.96 L3MBTL1 (0.58) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29340585 0.93 NPC1 (0.51) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29340582 0.93 NPC1 (0.51) NPC1L3MBTL1HSP90AA1TOP1CCR1
SCHEMBL29342049 0.85 MEN1 (0.45) NPC1L3MBTL1MEN1KMT2APPARA
SCHEMBL29342048 0.83 KMT2A (0.46) NPC1L3MBTL1MEN1KMT2APPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023058644-A9 COMPOUND, ORGANIC EL ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE 東レ株式会社 2024-07-18 WO disclosed