Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948680 | 0.84 | KIF11 (0.56) | MAPTKDM4EKIF11CYP1A2CYP2D6 | |
| SCHEMBL20434645 | 0.76 | KIF11 (0.58) | ARKDM4ETDP1KIF11PARP14 | |
| SCHEMBL13100678 | 0.75 | KIF11 (0.56) | MAPTKDM4EKIF11GABRPGABRD | |
| SCHEMBL27919630 | 0.72 | AR (0.66) | ARMAPTKDM4ETDP1KIF11 | |
| SCHEMBL3942114 | 0.72 | PDK2 (0.62) | ARKDM4ETDP1PLA2G7 | |
| SCHEMBL11806866 | 0.71 | AR (0.56) | ARKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL12750881 | 0.71 | PARP1 (0.54) | MAPTKDM4ECYP1A2GABRPGABRD | |
| SCHEMBL11814599 | 0.71 | AR (0.57) | ARMAPTKDM4ETDP1CYP1A2 | |
| SCHEMBL329557 | 0.70 | AR (0.62) | ARMAPTKDM4EKIF11PARP14 | |
| SCHEMBL1564051 | 0.69 | IDO1 (0.57) | MAPTKDM4ECYP1A2MEN1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |