SCHEMBL29341891

SCHEMBL29341891

N=S1(=O)CCC(n2cc(Br)cn2)CC1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.37
KDM5A P29375 1/20 0.36
WDR5 P61964 1/20 0.34
MPO P05164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20910160 0.87 ACHE (0.39) ACHEKDM5AWDR5MPO
SCHEMBL574364 0.81 ACHE (0.47) ACHEKDM5AWDR5MPO
SCHEMBL1404089 0.80
SCHEMBL29341892 0.80 KDM5A (0.36) ACHEKDM5AWDR5MPO
SCHEMBL16758445 0.79 ACHE (0.46) ACHEKDM5AWDR5MPO
SCHEMBL17121177 0.79 ACHE (0.46) ACHEKDM5AWDR5MPO
SCHEMBL1428115 0.75 IKBKE (0.44) KDM5A
SCHEMBL29090734 0.74 KDM5A (0.36) ACHEKDM5AWDR5MPO
SCHEMBL3117992 0.74 KDM5A (0.36) ACHEKDM5AWDR5MPO
SCHEMBL1427768 0.73 KDM5A (0.42) ACHEKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025034912-A9 COMPOUNDS FOR FGFR INHIBITION COGENT BIOSCIENCES, INC. (US) 2025-04-24 WO disclosed
WO-2025034912-A2 COMPOUNDS FOR FGFR INHIBITION COGENT BIOSCIENCES, INC. (US) 2025-02-13 WO disclosed
WO-2024151638-A2 COMPOUNDS FOR FGFRS INHIBITORS COGENT BIOSCIENCES, INC. (US) 2024-07-18 WO disclosed