Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341639 | 0.82 | KIF11 (0.41) | KIF11CYP2D6CYP2C9 | |
| SCHEMBL28273088 | 0.78 | CA1 (0.37) | CYP2C9 | |
| SCHEMBL10842487 | 0.76 | KIF11 (0.31) | KIF11 | |
| SCHEMBL24499756 | 0.71 | KIF11 (0.33) | KIF11 | |
| SCHEMBL29596950 | 0.71 | KIF11 (0.33) | KIF11 | |
| SCHEMBL465082 | 0.71 | KIF11 (0.34) | KIF11 | |
| SCHEMBL2457908 | 0.71 | KIF11 (0.44) | KIF11CYP2D6CYP2C9 | |
| SCHEMBL9342595 | 0.70 | KIF11 (0.38) | KIF11CYP2D6CYP2C9 | |
| SCHEMBL441131 | 0.70 | CA1 (0.44) | CYP2C9 | |
| SCHEMBL7141249 | 0.70 | CA1 (0.37) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | KIF11 1425/4885CYP2D6 2875/4885CYP2C9 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.