⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29081354 | 0.81 | MAP4K1 (0.36) | — | |
| SCHEMBL30469845 | 0.81 | MAP4K1 (0.36) | — | |
| SCHEMBL24365030 | 0.81 | MAP4K1 (0.36) | — | |
| SCHEMBL30470215 | 0.75 | MAP4K1 (0.34) | — | |
| SCHEMBL24365024 | 0.75 | MAP4K1 (0.34) | — | |
| SCHEMBL29081221 | 0.75 | MAP4K1 (0.34) | — | |
| SCHEMBL25321547 | 0.69 | MAP4K1 (0.38) | — | |
| SCHEMBL25321555 | 0.69 | MAP4K1 (0.38) | — | |
| SCHEMBL24364988 | 0.67 | MAP4K1 (0.36) | — | |
| SCHEMBL30469859 | 0.67 | MAP4K1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |