Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.36 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29081354 | 1.00 | MAP4K1 (0.36) | MAP4K1MAP4K3USP7 | |
| SCHEMBL30469845 | 1.00 | MAP4K1 (0.36) | MAP4K1MAP4K3USP7 | |
| SCHEMBL25321547 | 0.85 | MAP4K1 (0.38) | MAP4K1MAP4K3 | |
| SCHEMBL25321555 | 0.85 | MAP4K1 (0.38) | MAP4K1MAP4K3 | |
| SCHEMBL30469859 | 0.83 | MAP4K1 (0.36) | MAP4K1MAP4K3 | |
| SCHEMBL24364988 | 0.83 | MAP4K1 (0.36) | MAP4K1MAP4K3 | |
| SCHEMBL29344267 | 0.81 | — | — | |
| SCHEMBL25338709 | 0.80 | MAP4K1 (0.39) | MAP4K1MAP4K3 | |
| SCHEMBL25338713 | 0.80 | MAP4K1 (0.39) | MAP4K1MAP4K3 | |
| SCHEMBL25335603 | 0.76 | HTR3A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | MAP4K1 4775/4885MAP4K3 4599/4885USP7 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.