Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | EYA2 | O00167 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 4/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14462553 | 0.91 | TDP1 (0.61) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL12085022 | 0.89 | TRPA1 (0.40) | TDP1ALOX15BLMPMP22LMNA | |
| SCHEMBL1574695 | 0.89 | TDP1 (0.53) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL3639097 | 0.89 | TDP1 (0.53) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL3636303 | 0.86 | TDP1 (0.50) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL12191702 | 0.86 | TDP1 (0.55) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL2359794 | 0.86 | TDP1 (0.55) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL18412664 | 0.83 | BLM (0.36) | TDP1EYA2APPACEBLM | |
| SCHEMBL27434395 | 0.82 | CHRM2 (0.40) | TDP1ALOX15BLMPMP22LMNA | |
| SCHEMBL24864482 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |