SCHEMBL29344750

SCHEMBL29344750

COc1cc(CN(C)c2cc(Nc3cc(F)cc4c3OCCO4)nc3c(NC(=O)N[C@@H]4C[C@@H]4F)cnn23)cc(OC)c1OC

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 20/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29344747 0.82 P2RX7 (0.30)
SCHEMBL29344749 0.81 P2RX7 (0.33)
SCHEMBL29344744 0.81
Cenacitinib SCHEMBL23327405 0.81 TYK2 (0.54) TYK2
Cenacitinib SCHEMBL23327769 0.81 TYK2 (0.54) TYK2
Cenacitinib SCHEMBL23327413 0.81 TYK2 (0.54) TYK2
Cenacitinib SCHEMBL23327756 0.81 TYK2 (0.54) TYK2
Cenacitinib SCHEMBL23327489 0.81 TYK2 (0.54) TYK2
Cenacitinib SCHEMBL30548461 0.81 TYK2 (0.54) TYK2
Cenacitinib SCHEMBL30548441 0.81 TYK2 (0.54) TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151992-A1 PREPARATION OF A TYK2 INHIBITOR VENTYX BIOSCIENCES, INC. (US) 2024-07-18 WO disclosed