Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914521 | 1.00 | TDP1 (0.51) | TDP1USP30HSD17B10EPHX2KDM4E | |
| SCHEMBL30914527 | 1.00 | TDP1 (0.51) | TDP1USP30HSD17B10EPHX2KDM4E | |
| SCHEMBL9944501 | 0.86 | KMT2A (0.56) | TDP1HSD17B10EPHX2KDM4ENFKB1 | |
| SCHEMBL29077534 | 0.82 | TDP1 (0.53) | TDP1HSD17B10EPHX2KDM4ENFKB1 | |
| SCHEMBL1116600 | 0.82 | TDP1 (0.53) | TDP1HSD17B10EPHX2KDM4ENFKB1 | |
| SCHEMBL106877 | 0.82 | NPC1 (0.56) | TDP1HSD17B10KDM4ENFKB1NFKB2 | |
| SCHEMBL14460230 | 0.81 | RAB9A (0.56) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18231413 | 0.81 | TDP1 (0.59) | TDP1HSD17B10EPHX2KDM4ENFKB1 | |
| SCHEMBL29781372 | 0.81 | TDP1 (0.59) | TDP1HSD17B10EPHX2KDM4ENFKB1 | |
| SCHEMBL29781370 | 0.81 | TDP1 (0.59) | TDP1HSD17B10EPHX2KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4649082-A1 | PREPARATION OF A TYK2 INHIBITOR | Ventyx Biosciences, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |