SCHEMBL29346068

COCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCOCCOCCN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	FAP	Q12884	5/20	0.41

▸	FOLH1	Q04609	2/20	0.32

▸	TTR	P02766	2/20	0.31

▸	FURIN	P09958	1/20	0.31

▸	NPY1R	P25929	1/20	0.31

▸	NPY2R	P49146	1/20	0.31

▸	NPY4R	P50391	1/20	0.31

▸	NPY5R	Q15761	1/20	0.31

▸	SIRT2	Q8IXJ6	4/20	0.31

▸	GLP1R	P43220	2/20	0.31

▸	SIRT1	Q96EB6	2/20	0.31

▸	MAP1LC3B	Q9GZQ8	1/20	0.31

▸	SCTR	P47872	1/20	0.31

▸	PCSK9	Q8NBP7	1/20	0.30

▸	CYP3A4	P08684	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29340481	0.95	FAP (0.40)	FAPFURINNPY1RNPY2RNPY4R
SCHEMBL24864405	0.95	FAP (0.40)	FAPFURINNPY1RNPY2RNPY4R
SCHEMBL29346083	0.94	FAP (0.39)	FAPFOLH1TTRGLP1RSCTR
SCHEMBL24864498	0.94	FAP (0.40)	FAPSIRT2GLP1RSIRT1PCSK9
SCHEMBL24864507	0.93	FAP (0.40)	FAPFURINNPY1RNPY2RNPY4R
SCHEMBL29346082	0.92	FAP (0.40)	FAPFURINSIRT2GLP1RSIRT1
SCHEMBL24864625	0.91	FAP (0.38)	FAPTTRSIRT2GLP1RSIRT1
SCHEMBL24864380	0.91	FAP (0.40)	FAPTTRFURINSIRT2GLP1R
SCHEMBL24864408	0.90	FAP (0.40)	FAPFURINGLP1RSCTR
SCHEMBL29340522	0.90	FAP (0.39)	FAPFOLH1TTRSIRT2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024151890-A1	LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME	PROFOUNDBIO US CO. (US)	2024-07-18	—	—	WO	disclosed