Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18588233 | 1.00 | GAA (0.48) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL24533284 | 0.98 | GAA (0.50) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL4414727 | 0.91 | GAA (0.55) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL4409987 | 0.91 | GAA (0.55) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL4409617 | 0.89 | GAA (0.57) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL4411666 | 0.82 | GAA (0.62) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL4412014 | 0.82 | GAA (0.68) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL15010517 | 0.81 | GAA (0.47) | GAAKDM4ECTSDKDM5CPHF8 | |
| SCHEMBL762258 | 0.81 | LMNA (0.40) | GAALMNAPOLB | |
| SCHEMBL20801430 | 0.81 | LMNA (0.40) | GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |