Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20812485 | 0.92 | CRBN (0.65) | DDB1CRBNCHRM1CHRM2CHRM4 | |
| SCHEMBL29346538 | 0.87 | CRBN (0.52) | DDB1CRBNCHRM1CHRM2CHRM4 | |
| SCHEMBL29346391 | 0.80 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3OPRM1 | |
| SCHEMBL31730155 | 0.80 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3OPRM1 | |
| SCHEMBL30432757 | 0.76 | CRBN (0.62) | DDB1CRBNCHRM2OPRM1IKZF3 | |
| SCHEMBL29346395 | 0.76 | CRBN (0.85) | DDB1CRBNCHRM2OPRM1IKZF3 | |
| SCHEMBL17162095 | 0.76 | CRBN (0.62) | DDB1CRBNCHRM2OPRM1IKZF3 | |
| SCHEMBL22728747 | 0.75 | CRBN (0.57) | DDB1CRBNCHRM2OPRM1IKZF3 | |
| SCHEMBL31730111 | 0.75 | CRBN (0.66) | DDB1CRBNCHRM2OPRM1IKZF3 | |
| SCHEMBL29347351 | 0.75 | CRBN (0.66) | DDB1CRBNCHRM2OPRM1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |