Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.52 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29346418 | 0.87 | DDB1 (0.55) | CRBNDDB1OPRM1OPRD1OPRK1 | |
| SCHEMBL29346537 | 0.81 | OPRL1 (0.56) | OPRM1OPRD1OPRK1OPRL1CHRM2 | |
| SCHEMBL20812485 | 0.79 | CRBN (0.65) | CRBNDDB1OPRM1IKZF3CHRM2 | |
| SCHEMBL31730111 | 0.78 | CRBN (0.66) | CRBNDDB1OPRM1IKZF3CHRM2 | |
| SCHEMBL29347351 | 0.78 | CRBN (0.66) | CRBNDDB1OPRM1IKZF3CHRM2 | |
| SCHEMBL2217118 | 0.74 | OPRM1 (0.74) | OPRM1OPRD1OPRK1OPRL1CHRM2 | |
| SCHEMBL29346395 | 0.74 | CRBN (0.85) | CRBNDDB1OPRM1IKZF3CHRM2 | |
| SCHEMBL30910142 | 0.74 | OPRL1 (0.86) | OPRM1OPRD1OPRK1OPRL1CHRM2 | |
| SCHEMBL26092381 | 0.74 | OPRL1 (0.86) | OPRM1OPRD1OPRK1OPRL1CHRM2 | |
| SCHEMBL29346464 | 0.72 | DDB1 (0.65) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |