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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2934694

CN(C)CC(=O)N1CCC(C2C=CC(N)=C(C3=CCC(C)(C)CC3)N2)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.31

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TACR1 P25103 1/20 0.31
▸ HSP90AA1 P07900 1/20 0.31
▸ HSP90AB1 P08238 1/20 0.31
▸ CSF1R P07333 4/20 0.31
▸ RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5229553 0.83 CSF1R (0.33) CSF1R
Trifluoroacetic Acid SCHEMBL5227276 0.83 CSF1R (0.33) CSF1R
Trifluoroacetic Acid SCHEMBL5223002 0.75 CSF1R (0.33) CSF1R
Trifluoroacetic Acid SCHEMBL3172744 0.75 KIT (0.41) CSF1RRORC
Trifluoroacetic Acid SCHEMBL3082267 0.73 CSF1R (0.36) CSF1R
Trifluoroacetic Acid SCHEMBL3172735 0.70 KIT (0.40) HSP90AA1HSP90AB1CSF1R
SCHEMBL5233949 0.65 TACR1 (0.30) TACR1
SCHEMBL3172739 0.65 CSF1R (0.49) CSF1R
Trifluoroacetic Acid SCHEMBL4675377 0.64 CSF1R (0.33) CSF1R
SCHEMBL3082264 0.63 HSP90AA1 (0.33) HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2222298-A1 USE OF CFMS INHIBITOR FOR TREATING OR PREVENTING BONE CANCER AND THE BONE LOSS AND BONE PAIN ASSOCIATED WITH BONE CANCER Janssen Pharmaceutica N.V. (BE) 2010-09-01 — — EP disclosed
WO-2009058801-A1 USE OF CFMS INHIBITOR FOR TREATING OR PREVENTING BONE CANCER AND THE BONE LOSS AND BONE PAIN ASSOCIATED WITH BONE CANCER JANSSEN PHARMACEUTICA, N.V. (BE) 2009-05-07 — — WO disclosed