Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5223002 | 0.81 | CSF1R (0.33) | CSF1R | |
| SCHEMBL5138542 | 0.77 | KIT (0.32) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL5227276 | 0.75 | CSF1R (0.33) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL5229553 | 0.75 | CSF1R (0.33) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL3167701 | 0.67 | KIT (0.43) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL16594467 | 0.67 | CSF1R (0.34) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL2944022 | 0.66 | CSF1R (0.35) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL2942019 | 0.65 | CSF1R (0.41) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL3167687 | 0.65 | KIT (0.41) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL2934694 | 0.64 | TACR1 (0.31) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951234-A2 | METHOD OF INHIBITING FLT3 KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007048088-A2 | METHOD OF INHIBITING FLT3 KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-04-26 | — | — | WO | disclosed |