SCHEMBL29347019

SCHEMBL29347019

C=CCC1(CN)CCN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
CYP11B2 P19099 1/20 0.35
USP30 Q70CQ3 1/20 0.34
RORC P51449 3/20 0.34
SCD5 Q86SK9 1/20 0.34
HDAC2 Q92769 1/20 0.34
NR1H2 P55055 1/20 0.33
ACACB O00763 2/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
EPHX2 P34913 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31068605 0.88 USP2 (0.38) USP2SMN1; SMN2OPRD1OPRK1CYP11B2
SCHEMBL18309957 0.83 USP2 (0.41) USP2SMN1; SMN2OPRD1OPRK1CYP11B2
SCHEMBL29347021 0.83 TGM2 (0.38) USP2SMN1; SMN2CYP11B2USP30RORC
SCHEMBL3494732 0.82 USP2 (0.43) USP2SMN1; SMN2OPRD1OPRK1NR1H2
SCHEMBL18418212 0.81 USP2 (0.50) USP2SMN1; SMN2OPRD1OPRK1NR1H2
SCHEMBL24854181 0.81 USP2 (0.39) USP2SMN1; SMN2OPRD1OPRK1CYP11B2
SCHEMBL30289446 0.81 USP2 (0.42) USP2SMN1; SMN2OPRD1OPRK1NR1H2
SCHEMBL31695027 0.81 USP2 (0.39) USP2SMN1; SMN2OPRD1OPRK1CYP11B2
SCHEMBL31695034 0.81 USP2 (0.39) USP2SMN1; SMN2OPRD1OPRK1CYP11B2
SCHEMBL17763768 0.80 USP2 (0.40) USP2SMN1; SMN2OPRD1OPRK1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed