Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 8/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23540861 | 0.96 | DDB1 (0.52) | DDB1CRBNHDAC8IKZF1IKZF2 | |
| SCHEMBL23541289 | 0.96 | DDB1 (0.52) | DDB1CRBNHDAC8IKZF1IKZF2 | |
| SCHEMBL31397073 | 0.92 | DDB1 (0.51) | DDB1CRBNHDAC8IKZF1IKZF2 | |
| SCHEMBL22502565 | 0.89 | DDB1 (0.50) | DDB1CRBNIKZF1IKZF2 | |
| SCHEMBL31397215 | 0.88 | DDB1 (0.49) | DDB1CRBNHDAC8IKZF1IKZF2 | |
| SCHEMBL31068575 | 0.88 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL22525513 | 0.88 | DDB1 (0.49) | DDB1CRBNHDAC8IKZF1IKZF2 | |
| SCHEMBL25036957 | 0.86 | DDB1 (0.51) | DDB1CRBNHDAC8IKZF1IKZF2 | |
| SCHEMBL23540339 | 0.86 | DDB1 (0.41) | DDB1CRBNHDAC8IKZF1IKZF2 | |
| SCHEMBL23540196 | 0.85 | DDB1 (0.40) | DDB1CRBNHDAC8IKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388593-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2025-12-25 | — | — | US | disclosed |
| EP-4650348-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388593-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | CRBN, CUL1, CBL | DDB1 2368/4885CRBN 1/4885HDAC8 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.